Demonstration of tenascin‐like immunoreactivity in rabbit corneal wounds

Abstract

Tenascin, a novel extracellular matrix protein, was demonstrated immunohistochemically in rabbit corneas that had healed after anterior keratectomy. Tenascin-like immunofluorescence (T-LI) appeared in the corneal stroma at the wound area only. The wound edge showed the most intense specific fluorescence. The corneal epithelium, in general, displayed a moderate T-LI. Wounding did not induce any change in epithelial T-LI or T-LI located in the stroma outside the wound.