Adherence to Mediterranean diet and risk of developing diabetes: prospective cohort study
Top Cited Papers
Open Access
- 29 May 2008
- Vol. 336 (7657), 1348-1351
- https://doi.org/10.1136/bmj.39561.501007.be
Abstract
Objective To assess the relation between adherence to a Mediterranean diet and the incidence of diabetes among initially healthy participants. Design Prospective cohort study with estimates of relative risk adjusted for sex, age, years of university education, total energy intake, body mass index, physical activity, sedentary habits, smoking, family history of diabetes, and personal history of hypertension. Setting Spanish university department. Participants 13 380 Spanish university graduates without diabetes at baseline followed up for a median of 4.4 years. Main outcome measures Dietary habits assessed at baseline with a validated 136 item food frequency questionnaire and scored on a nine point index. New cases of diabetes confirmed through medical reports and an additional detailed questionnaire posted to those who self reported a new diagnosis of diabetes by a doctor during follow-up. Confirmed cases of type 2 diabetes. Results Participants who adhered closely to a Mediterranean diet had a lower risk of diabetes. The incidence rate ratios adjusted for sex and age were 0.41 (95% confidence interval 0.19 to 0.87) for those with moderate adherence (score 3-6) and 0.17 (0.04 to 0.75) for those with the highest adherence (score 7-9) compared with those with low adherence (score Conclusion Adherence to a Mediterranean diet is associated with a reduced risk of diabetes.This publication has 47 references indexed in Scilit:
- Modified Mediterranean diet and survival after myocardial infarction: the EPIC-Elderly studyEuropean Journal of Epidemiology, 2007
- Incidence of new-onset diabetes and impaired fasting glucose in patients with recent myocardial infarction and the effect of clinical and lifestyle risk factorsThe Lancet, 2007
- Components of the mediterranean-type food pattern and serum inflammatory markers among patients at high risk for cardiovascular diseaseEuropean Journal of Clinical Nutrition, 2007
- Protective mechanisms of the Mediterranean diet in obesity and type 2 diabetesThe Journal of Nutritional Biochemistry, 2007
- Anti-inflammatory effect of virgin olive oil in stable coronary disease patients: a randomized, crossover, controlled trialEuropean Journal of Clinical Nutrition, 2007
- Obesity and Diabetes in the Developing World — A Growing ChallengeThe New England Journal of Medicine, 2007
- Lifestyle, Mediterranean diet and survival in European post-myocardial infarction patientsEuropean Journal of Preventive Cardiology, 2006
- Modified Mediterranean diet and survival: EPIC-elderly prospective cohort studyBMJ, 2005
- Effect of a Mediterranean-Style Diet on Endothelial Dysfunction and Markers of Vascular Inflammation in the Metabolic SyndromeJama-Journal Of The American Medical Association, 2004
- Monounsaturated Fatty Acid Diets Improve Glycemic Tolerance through Increased Secretion of Glucagon-Like Peptide-1Endocrinology, 2001