A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation
- 31 March 2007
- journal article
- clinical trial
- Published by Elsevier BV in Molecular Immunology
- Vol. 44 (8), 1835-1844
- https://doi.org/10.1016/j.molimm.2006.10.005
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcomeBlood, 2006
- The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohortsJournal of Medical Genetics, 2005
- Mutations in CD46, a complement regulatory protein, predispose to atypical HUSTrends in Molecular Medicine, 2004
- Haemolytic uraemic syndrome and mutations of the factor H gene: a registry-based study of German speaking countriesJournal of Medical Genetics, 2003
- CCP1–4 of the C4b-binding protein α-chain are required for factor I mediated cleavage of complement factor C3bMolecular Immunology, 2003
- Hydrogen peroxide as second messenger in lymphocyte activationNature Immunology, 2002
- The molecular basis of hereditary complement factor I deficiency.JCI Insight, 1996
- Processing of human factor I in COS-1 cells co-transfected with factor I and paired basic amino acid cleaving enzyme (PACE) cDNAMolecular Immunology, 1995
- The Organization of the Human Complement Factor I Gene (IF): A Member of the Serine Protease Gene FamilyGenomics, 1994
- Complement factor I deficiency with recurrent aseptic meningitisArchives of Internal Medicine, 1993