Biological Basis of Determinants of Health
- 1 March 2005
- journal article
- review article
- Published by American Public Health Association in American Journal of Public Health
- Vol. 95 (3), 389-392
- https://doi.org/10.2105/ajph.2003.033324
Abstract
Clinical medicine and health policy planning find common cause as they seek to define the determinants of health. There is substantial recent interest in the social ecology in which health is embedded. However, biology is where these contributing environmental factors are translated. I provide a new conceptual framework for the biological determinants of health. The old public health rubric of host, agent, and environment as the features that define the root elements of health is an impoverished scheme, because it does not represent our new appreciation of genetic and aging contributions to phenotypic health. I propose genes, external agency, internal agency, and aging as more operationally helpful determinants that effectively describe the biological experience of the organism. This scheme has the advantage of differentiating those agencies that are practically approachable, and therefore deserving of increased attention and investment, and those that are currently intractable.Keywords
This publication has 28 references indexed in Scilit:
- Influences On The Health Of Populations: A Closer LookHealth Affairs, 2002
- Medicare Beneficiaries’ Costs Of Care In The Last Year Of LifeHealth Affairs, 2001
- The Ecology of Medical Care RevisitedThe New England Journal of Medicine, 2001
- Genetics of AgingScience, 1997
- How Fast Do We Age? Exercise Performance Over Time as a BiomarkerThe Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 1996
- Muscle Strength and Mobility as Predictors of Survival in 75–84 - Year - old PeopleAge and Ageing, 1995
- Cardiovascular changes with age and exerciseScandinavian Journal of Medicine & Science in Sports, 1995
- Order and complexity in dynamical systems: Homeodynamics as a generalized mechanics for biologyMathematical and Computer Modelling, 1994
- Actual Causes of Death in the United StatesJAMA, 1993
- Longevity Is Moderately Heritable in a Sample of Danish Twins Born 1870-1880Journal of Gerontology, 1993