Gastric MALT lymphoma with t(14;18)(q32;q21) involving IGH and BCL2 genes that responded to Helicobacter pylori eradication
- 28 September 2007
- journal article
- case report
- Published by BMJ in Journal of Clinical Pathology
- Vol. 60 (10), 1171-1173
- https://doi.org/10.1136/jcp.2007.048207
Abstract
Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is genetically characterised by the recurrent translocations t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH, t(14;18)(q32;q21)/IGH-MALT1 and t(3;14)(p14;q32)/FOXP1-IGH.1 2 Recent evidence suggests that at least some of these translocations may be associated with distinct clinicopathological features.1 3 The t(14;18)(q32;q21)/IGH-BCL2 is found in the majority of follicular lymphomas and some diffuse large B-cell lymphomas.4 However, MALT lymphomas carrying this translocation are extremely rare and their clinical features are virtually unknown.Keywords
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