HIV transmission in sexual networks: an empirical analysis
Open Access
- 22 June 1995
- journal article
- research article
- Published by The Royal Society in Proceedings. Biological sciences
- Vol. 260 (1359), 237-244
- https://doi.org/10.1098/rspb.1995.0086
Abstract
Risk behaviour and egocentric sexual network data collected from a large random sample of young gay men in San Francisco were analysed to assess the importance of sexual mixing (i.e. sexual networks) in the acquisition of HIV. These data were collected in 1993, during wave one of a longitudinal cohort study of HIV transmission in gay men; the seroprevalence level in the sample was 18%. We identify recent sexual mixing patterns and we demonstrate that seropositives and seronegatives have very different agestratified sexual mixing patterns. We show that sexual mixing can explain the current seroprevalence patterns in the young gay community; seroprevalence levels in risk groups reflect the degree of sexual mixing with the older (and more heavily infected) age group. Our results suggest that seropositives became infected with HIV not simply owing to an increased rate of acquisition of sex partners, but also as a result of their sexual mixing pattern. We develop and apply a simple methodology that uses the sexual network data in combination with risk behaviour data to estimate the future number of seroconverters. Our methodology is validated by testing our predictions against the observed seroconversion data collected during wave two of the cohort study in 1994. Our analyses empirically demonstrate (for the first time) the significance of sexual mixing as a risk factor for HIV transmission.This publication has 19 references indexed in Scilit:
- Exploratory data analysis of three sexual behavior surveys: implications for HIV-1 transmission in the U. KPhilosophical Transactions B, 1993
- Modeling HIV Transmission and AIDS in the United StatesPublished by Springer Science and Business Media LLC ,1992
- Estimation of a preference matrix for women's choice of male sexual partner according to rate of partner change, using partner notification dataMathematical Biosciences, 1991
- Mixing ecology and epidemiologyProceedings. Biological sciences, 1991
- Statistical Data Analysis in the Computer AgeScience, 1991
- A General Solution of the Problem of Mixing of Subpopulations and its Application to Risk- and Age-Structured Epidemic Models for the Spread of AIDSMathematical Medicine and Biology, 1991
- Drugs, sex and HIV : a mathematical model for New York CityPhilosophical Transactions B, 1991
- The Effect of Social Mixing Patterns on the Spread of AIDSLecture Notes in Biomathematics, 1989
- On the transmission dynamics of HIVMathematical Biosciences, 1988
- Gonorrhea Transmission Dynamics and ControlPublished by Springer Science and Business Media LLC ,1984