Anemia and heart failure
- 1 March 2009
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Current Opinion in Cardiology
- Vol. 24 (2), 172-178
- https://doi.org/10.1097/hco.0b013e328324ecec
Abstract
The earlier enthusiasm for raising hemoglobin in heart failure has been followed by skepticism and concern of potential harm from using erythropoiesis-stimulating agents (ESAs). Several recent studies have confirmed the high prevalence and prognostic role of anemia and have shown encouraging signals of the safety of using ESAs in heart failure and potential benefit that may be related to nonhematopoietic effects of ESAs. In addition, recent studies have also suggested a potential beneficial role of iron replacement in heart failure. Despite the encouraging findings of these preliminary studies, the future role of ESAs and iron replacement will be determined by ongoing randomized placebo-controlled studies.Keywords
This publication has 72 references indexed in Scilit:
- Anemia and Heart Failure: A Community StudyAmerican Journal Of Medicine, 2008
- Relation of Low Hemoglobin and Anemia to Morbidity and Mortality in Patients Hospitalized With Heart Failure (Insight from the OPTIMIZE-HF Registry)The American Journal of Cardiology, 2008
- Non-cardiac comorbidities in chronic heart failureHeart, 2007
- Intravenous Iron Alone for the Treatment of Anemia in Patients With Chronic Heart FailureJournal of the American College of Cardiology, 2006
- The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration?Blood, 2006
- Prevalence of anemia and effects on mortality in patients with heart failureAmerican Heart Journal, 2005
- Are hematinic deficiencies the cause of anemia in chronic heart failure?American Heart Journal, 2004
- The prognostic importance of anemia in patients with heart failureAmerican Journal Of Medicine, 2003
- Anaemia in chronic heart failure: what is its frequency in the UK and its underlying causes?Heart, 2002
- IV. NKF-K/DOQI Clinical Practice Guidelines for Anemia of Chronic Kidney Disease: Update 2000American Journal of Kidney Diseases, 2001