Relevance of the Application of Pharmacokinetic-Pharmacodynamic Modelling Concepts in Drug Development
- 1 April 1997
- journal article
- review article
- Published by Springer Science and Business Media LLC in Clinical Pharmacokinetics
- Vol. 32 (4), 259-267
- https://doi.org/10.2165/00003088-199732040-00001
Abstract
No abstract availableThis publication has 25 references indexed in Scilit:
- Role of Pharmacokinetic-Pharmacodynamic Principles in Rational and Cost-Effective Drug DevelopmentTherapeutic Drug Monitoring, 1996
- Remifentanil Versus AlfentanilAnesthesiology, 1996
- Role of Patient Compliance in Clinical PharmacokineticsClinical Pharmacokinetics, 1994
- Comparison of four basic models of indirect pharmacodynamic responsesJournal of Pharmacokinetics and Biopharmaceutics, 1993
- Pharmacodynamic System Analysis of the Biophase Level Predictor and the Transduction FunctionJournal of Pharmaceutical Sciences, 1992
- Differences in intrinsic efficacy of benzodiazepines are reflected in their concentration‐EEG effect relationshipBritish Journal of Pharmacology, 1992
- Pharmacokinetic-Pharmacodynamic Modelling of the Interaction between Flumazenil and Midazolam in Volunteers by Aperiodic EEG AnalysisClinical Pharmacokinetics, 1991
- A System Approach to Pharmacodynamics. Ill: An Algorithm and Computer Program, COLAPS, for Pharmacodynamic ModelingJournal of Pharmaceutical Sciences, 1991
- Pharmacokinetic-pharmacodynamic modeling of CNS drug effects: An overviewPharmacology & Therapeutics, 1988
- Comparative Pharmacokinetics of Coumarin Anticoagulants X: Relationship between Distribution, Elimination, and Anticoagulant Action of WarfarinJournal of Pharmaceutical Sciences, 1974