Morphometric Spatial Patterns Differentiating Boys With Fragile X Syndrome, Typically Developing Boys, and Developmentally Delayed Boys Aged 1 to 3 Years

Abstract
Human brain maturation is a complex process that can now be examined in detail using in vivo neuroimaging techniques.1 Early neuroimaging investigations focused on region, lobe, or total brain volumes.1 However, more recent studies have begun to examine brain structures using finer voxelwise resolution and temporal dynamics. These new approaches have proven useful in advancing our understanding of associations between cognition and healthy brain development.2