Penetration of Amphotericin B Lipid Formulations into Pleural Effusion
- 1 November 2007
- journal article
- clinical trial
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 51 (11), 4211-4213
- https://doi.org/10.1128/aac.01087-07
Abstract
The penetration of the amphotericin B (AMB) lipid formulations (liposomal AMB, AMB colloidal dispersion, and AMB lipid complex formulations) into pleural effusions in seven critically ill patients was assessed. AMB was detected in all pleural effusion samples at concentrations ranging from 0.02 to 0.43 μg/ml. The penetration ratio was 3 to 44%.Keywords
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