Three-dimensional architecture of a polytene nucleus
- 1 April 1983
- journal article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 302 (5910), 676-681
- https://doi.org/10.1038/302676a0
Abstract
The three-dimensional chromosome topography in an intact nucleus has been determined using fluorescently stained Drosophila polytene chromosomes, optical fluorescence microscopy and newly developed, generally applicable, cellular image reconstruction techniques. The folding pattern is a complex mixture of parallel chromosomal segments and intertwined coils and shows extensive interaction of the chromosomes with the nuclear envelope.Keywords
This publication has 21 references indexed in Scilit:
- Structure of the cro repressor from bacteriophage λ and its interaction with DNANature, 1981
- Structure of catabolite gene activator protein at 2.9 Å resolution suggests binding to left-handed B-DNANature, 1981
- Crystal structure analysis of a complete turn of B-DNANature, 1980
- A low resolution structure for the histone core of the nucleosomeNature, 1980
- High-salt d(CpGpCpG), a left-handed Z′ DNA double helixNature, 1980
- Metaphase chromosome structure: Evidence for a radial loop modelCell, 1979
- A Direct Approach to the Structure of Eukaryotic ChromosomesCold Spring Harbor Symposia on Quantitative Biology, 1978
- X-ray and Electron Microscope Analyses of Crystals of Nucleosome CoresCold Spring Harbor Symposia on Quantitative Biology, 1978
- Structure of ChromatinAnnual Review of Biochemistry, 1977
- Nucleotide sequence of bacteriophage φX174 DNANature, 1977