B7-H4 Expression in Human Melanoma: Its Association with Patients' Survival and Antitumor Immune Response
Open Access
- 15 May 2011
- journal article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 17 (10), 3100-3111
- https://doi.org/10.1158/1078-0432.ccr-10-2268
Abstract
Purpose: Cancers have developed a number of strategies to escape immune responses including the differential expression of costimulatory molecules of the B7 family. B7-H3 and B7-H4 have recently been described in different tumor entities but the relevance for melanoma has not yet been studied so far.Keywords
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This publication has 57 references indexed in Scilit:
- Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomasLaboratory Investigation, 2010
- Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancerBMC Cancer, 2009
- B7‐H3 is a potent inhibitor of human T‐cell activation: No evidence for B7‐H3 and TREML2 interactionEuropean Journal of Immunology, 2009
- Costimulatory and coinhibitory receptors in anti‐tumor immunityImmunological Reviews, 2009
- Fine tuning the immune response through B7‐H3 and B7‐H4Immunological Reviews, 2009
- Expression of Immunosuppresive B7-H3 Ligand by Hormone-Treated Prostate Cancer Tumors and MetastasesClinical Cancer Research, 2009
- Tumor Cell and Tumor Vasculature Expression of B7-H3 Predict Survival in Clear Cell Renal Cell CarcinomaClinical Cancer Research, 2008
- Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responsesProceedings of the National Academy of Sciences of the United States of America, 2008
- B7-H4 expression in renal cell carcinoma and tumor vasculature: Associations with cancer progression and survivalProceedings of the National Academy of Sciences of the United States of America, 2006
- B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinomaThe Journal of Experimental Medicine, 2006