Neonatal Nonhemolytic Jaundice

Abstract

NUMEROUS causes of nonhemolytic jaundice are encountered during the first month of life. Two groups of patients are distinguished: those with unconjugated and those with conjugated hyperbilirubinemia.Unconjugated Hyperbilirubinemia (Table 1)"Physiologic jaundice" is the most common form of unconjugated, nonhemolytic hyperbilirubinemia in the neonatal period. Maximum serum bilirubin concentration occurs at three to four days of age (mean, 6 to 8 mg per 100 ml) and rapidly diminishes thereafter. Certain Asian groups (Chinese, Indian and Malaysian), some American Indians and some population groups in Greece have higher peaks of "physiologic" hyperbilirubinemia. "Physiologic Jaundice" in the premature infant reaches a . . .