Small cell carcinoma of the gallbladder: report of two cases.
- 1 September 1999
- journal article
- case report
- Published by Springer Science and Business Media LLC in Pathology and Oncology Research
- Vol. 5 (3), 235-238
- https://doi.org/10.1053/paor.1999.0216
Abstract
Two Taiwanese patients with gallbladder small cell carcinoma are reported. One is a 79 year-old male, the other, a 86 year-old female. They both presented with the symptom/signs of acute cholecystitis and underwent cholecystectomy. An intramural mass in the gallbladder neck region was found in the first patient, while the second patient had a transmural indurated tumor in the gallbladder body with extension to the neck region. Characteristic histological and immunohistochemical features of small cell carcinoma were present in both, and electron dense neurosecretory granules were identified in the second. To our knowledge, the second patient is the oldest ever reported. The first patient received chemotherapy directed toward the initial erroneous diagnosis of non-Hodgkin s lymphoma and developed liver metastasis in two months. The second patient did not receive chemotherapy due to her poor general condition and local recurrence occurred in six weeks. Both passed away three and five months after surgery, respectively.Keywords
This publication has 12 references indexed in Scilit:
- Unusual malignant epithelial tumors of the gallbladder.1996
- Small cell carcinoma of gallbladder: report of two cases.1996
- Carcinoid Tumor of the Gall Bladder.Internal Medicine, 1996
- Small-cell carcinoma combined with adenocarcinoma of the gallbladder. A case report with immunohistochemical and flow cytometric studies.1994
- Primary low‐grade B‐cell lymphoma of the mucosa‐associated lymphoid tissue arising in the gallbladderHistopathology, 1992
- Small-Cell Carcinoma of Gallbladder: An Immunocytochemical and Ultrastructural StudyPathology - Research and Practice, 1991
- Endocrine Cell Carcinoma (Carcinoid) of the GallbladderThe American Journal of Surgical Pathology, 1989
- Endocrine Tumors of the Gastrointestinal Tract: Classification, Function and Biological BehaviorPublished by Springer Science and Business Media LLC ,1988
- Gastroenteropancreatic Neuroendocrine Tumors: A Histochemical and Immunohistochemical Study of Epithelial (keratin proteins, carcinoembryonic antigen) and Neuroendocrine (neuron-specific enolase, bombesin and chromogranin) Markers in Foregut, Midgut, and Hindgut TumorsAmerican Journal of Clinical Pathology, 1986
- Unusual types of gallbladder carcinoma. A report of 16 cases.1981