Association between Helicobacter pylori infection and interleukin 1 polymorphism predispose to CpG island methylation in gastric cancer
Open Access
- 1 April 2007
- Vol. 56 (4), 595-597
- https://doi.org/10.1136/gut.2006.113258
Abstract
We obtained surgical specimens and their corresponding peripheral blood from 98 consecutive patients with gastric cancer admitted to Queen Mary Hospital, Hong Kong. This study was approved by the ethics committee. The …Keywords
This publication has 10 references indexed in Scilit:
- Eradication of Helicobacter pylori infection reverses E-cadherin promoter hypermethylationGut, 2006
- High Levels of Aberrant DNA Methylation in Helicobacter pylori–Infected Gastric Mucosae and its Possible Association with Gastric Cancer RiskClinical Cancer Research, 2006
- Aberrant CpG Island Hypermethylation of Chronic Gastritis, in Relation to Aging, Gender, Intestinal Metaplasia, and Chronic InflammationThe American Journal of Pathology, 2003
- Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancerGut, 2003
- Interleukin 1β polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in JapanGastroenterology, 2002
- Interleukin-1 polymorphisms associated with increased risk of gastric cancerNature, 2000
- Methylation-Dependent Gene Silencing Induced by Interleukin 1β via Nitric Oxide ProductionThe Journal of Experimental Medicine, 1999
- Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strainsGut, 1997
- Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.Proceedings of the National Academy of Sciences of the United States of America, 1996
- Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeatHuman Genetics, 1993