Efficient and Allele-Specific Genome Editing of Disease Loci in Human iPSCs
Open Access
- 1 March 2015
- journal article
- Published by Elsevier BV in Molecular Therapy
- Vol. 23 (3), 570-577
- https://doi.org/10.1038/mt.2014.226
Abstract
No abstract availableKeywords
This publication has 45 references indexed in Scilit:
- Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis PatientsCell Stem Cell, 2013
- Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditionsStem Cell Research, 2013
- One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome EngineeringCell, 2013
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing SpecificityCell, 2013
- Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editingScientific Reports, 2013
- Optimization of scarless human stem cell genome editingNucleic Acids Research, 2013
- DNA targeting specificity of RNA-guided Cas9 nucleasesNature Biotechnology, 2013
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cellsNature Biotechnology, 2013
- Enhanced Efficiency of Human Pluripotent Stem Cell Genome Editing through Replacing TALENs with CRISPRsCell Stem Cell, 2013
- Efficient drug screening and gene correction for treating liver disease using patient-specific stem cellsHepatology, 2013