Macrolide Resistance Mediated by a Bifidobacterium breve Membrane Protein
Open Access
- 1 October 2005
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 49 (10), 4379-4381
- https://doi.org/10.1128/aac.49.10.4379-4381.2005
Abstract
A gene coding for a hypothetical membrane protein from Bifidobacterium breve was expressed in Lactococcus lactis . Immunoblotting demonstrated that this protein is located in the membrane. Phenotypical changes in sensitivity towards 21 antibiotics were determined. The membrane protein-expressing cells showed higher levels of resistance to several macrolides.Keywords
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