Data mining of NCI's anticancer screening database reveals mitochondrial complex I inhibitors cytotoxic to leukemia cell lines
- 1 February 2007
- journal article
- Published by Elsevier BV in Biochemical Pharmacology
- Vol. 73 (3), 331-340
- https://doi.org/10.1016/j.bcp.2006.10.005
Abstract
No abstract availableKeywords
This publication has 74 references indexed in Scilit:
- Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cellsApoptosis, 2005
- Disruption of Mitochondrial Function during Apoptosis Is Mediated by Caspase Cleavage of the p75 Subunit of Complex I of the Electron Transport ChainCell, 2004
- Dependence on electron transport chain function and intracellular signaling of genomic responses in SH-SY5Y cells to the mitochondrial neurotoxin MPP+Experimental Neurology, 2003
- The Proton-Translocating NADH−Quinone Oxidoreductase in the Respiratory Chain: The Secret UnlockedBiochemistry, 2003
- Do Structurally Similar Molecules Have Similar Biological Activity?Journal of Medicinal Chemistry, 2002
- Developmental Therapeutics Program at the NCI: molecular target and drug discovery processLeukemia, 2002
- Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 å in iceJournal of Molecular Biology, 1998
- Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductaseFEBS Letters, 1993
- Complex I and Complex III of Mitochondria Have Common Inhibitors Acting as Ubiquinone AntagonistsBiochemical and Biophysical Research Communications, 1993
- Electron transfer properties of NADH: Ubiquinone reductase in the ND1/3460 and the ND4/11778 mutations of the Leber hereditary optic neuroretinopathy (LHON)FEBS Letters, 1991