Quality of Life in Patients with Knee Osteoarthritis: A Commentary on Nonsurgical and Surgical Treatments
Open Access
- 13 November 2013
- journal article
- Published by Bentham Science Publishers Ltd. in The Open Orthopaedics Journal
- Vol. 7 (1), 619-623
- https://doi.org/10.2174/1874325001307010619
Abstract
Knee osteoarthritis (OA) has a significant negative impact on health-related quality of life (HRQoL). Identification of therapies that improve HRQoL in patients with knee OA may mitigate the clinical, economic, and social burden of this disease. The purpose of this commentary is to report the impact of knee OA on HRQoL, describe the change in HRQoL attributable to common knee OA interventions, and summarize findings from clinical trials of a promising therapy. Nonsurgical therapies do not reliably modify HRQoL in knee OA patients given their general inability to alleviate physical manifestations of OA. Surgical knee OA interventions generally result in good to excellent patient outcomes. However, there are significant barriers to considering surgery, which limits clinical utility. Therapies that most effectively control OA-related pain with a low risk: benefit ratio will likely have the greatest benefit on HRQoL with greater rates of patient adoption. Initial clinical trial findings suggest that less invasive joint unloading implants hold promise in bridging the therapeutic gap between nonsurgical and surgical treatments for the knee OA patient.Keywords
This publication has 62 references indexed in Scilit:
- Customized Foot Insoles Have a Positive Effect on Pain, Function, and Quality of Life in Patients with Medial Knee OsteoarthritisJournal of the American Podiatric Medical Association, 2013
- The implementation of a community-based aerobic walking program for mild to moderate knee osteoarthritis: A knowledge translation randomized controlled trial: Part II: Clinical outcomesBMC Public Health, 2012
- Longitudinal impact of joint pain comorbidity on quality of life and activity levels in knee osteoarthritis: data from the Osteoarthritis InitiativeRheumatology, 2012
- The effectiveness of a self-management program on quality of life for knee osteoarthritis (OA) patientsArchives of Gerontology and Geriatrics, 2012
- Cartilage in normal and osteoarthritis conditionsBest Practice & Research Clinical Rheumatology, 2008
- A patient‐centered perspective on surgery avoidance for hip or knee arthritis: Lessons for the futureArthritis Care & Research, 2007
- Increased joint loads during walking – A consequence of pain relief in knee osteoarthritisThe Knee, 2006
- Brace treatment for osteoarthritis of the knee: a prospective randomized multi-centre trialOsteoarthritis and Cartilage, 2006
- Health related quality of life in multiple musculoskeletal diseases: SF-36 and EQ-5D in the DMC3 studyAnnals Of The Rheumatic Diseases, 2004
- The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritisHealth and Quality of Life Outcomes, 2003