Recombinant Factor VIIa in the Treatment of Bleeding
Open Access
- 1 January 2004
- journal article
- review article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 121 (1), 124-137
- https://doi.org/10.1309/d0g0-c96v-05cj-5b4j
Abstract
Recombinant factor VIIa (rFVIIa) has become available for treating people with hemophilia with inhibitors who experience bleeding or require surgery. It has become apparent that rFVIIa is useful in controlling bleeding in a variety of clinical situations. This review attempts to collate and summarize the nonhemophilia applications of rFVIIa. The theoretical mechanism for the coagulation and hemostatic effects of rFVIIa are discussed. The dosage and clinical administration are described.Keywords
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