What makes us tick? Functional and neural mechanisms of interval timing
Top Cited Papers
- 15 September 2005
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature Reviews Neuroscience
- Vol. 6 (10), 755-765
- https://doi.org/10.1038/nrn1764
Abstract
Time is a fundamental dimension of life. It is crucial for decisions about quantity, speed of movement and rate of return, as well as for motor control in walking, speech, playing or appreciating music, and participating in sports. Traditionally, the way in which time is perceived, represented and estimated has been explained using a pacemaker-accumulator model that is not only straightforward, but also surprisingly powerful in explaining behavioural and biological data. However, recent advances have challenged this traditional view. It is now proposed that the brain represents time in a distributed manner and tells the time by detecting the coincidental activation of different neural populations.Keywords
This publication has 98 references indexed in Scilit:
- Cortico-striatal circuits and interval timing: coincidence detection of oscillatory processesCognitive Brain Research, 2004
- Timing speech: a review of lesion and neuroimaging findingsCognitive Brain Research, 2004
- Coordination of circadian timing in mammalsNature, 2002
- Timing and Foraging: Gibbon's Scalar Expectancy Theory and Optimal Patch ExploitationLearning and Motivation, 2002
- Choline Uptake in the Frontal Cortex Is Proportional to the Absolute Error of a Temporal Memory Translation Constant in Mature and Aged RatsLearning and Motivation, 2002
- Numerical representation for action in the parietal cortex of the monkeyNature, 2002
- Time estimation in schizophrenia: an fMRI study at adjusted levels of difficultyNeuroReport, 2001
- The Search for Simplicity: A Fundamental Cognitive Principle?The Quarterly Journal of Experimental Psychology Section A, 1999
- Neuropharmacology of timing and time perceptionCognitive Brain Research, 1996
- Neural dynamics of adaptive timing and temporal discrimination during associative learningNeural Networks, 1989