History of spine surgery for tuberculous spondylodiscitis
- 28 October 2015
- journal article
- review article
- Published by Springer Science and Business Media LLC in Der Unfallchirurg
- Vol. 118 (S1), 19-27
- https://doi.org/10.1007/s00113-015-0093-9
Abstract
For those stricken with tuberculosis, a disease that was present in ancient times, treatment was originally limited to conservative treatment including high altitude, fresh air, rest, and immobilization, manual reduction devices, and surgical procedures. Mortality and morbidity were high until the advent of antitubercular chemotherapy in the 1940s. Today multidrug regimen enable good disease clearance and also make direct surgical debridement without complications possible. Antitubercular drugs have reduced mortality by 72.5%. Surgical intervention is reserved for selected situations. Früher waren die Behandlungsmöglichkeiten für von Tuberkulose betroffene Menschen bis auf homöopathische Ansätze bzw. manuelle Apparaturen und operative Verfahren außerordentlich begrenzt, und bis zur Einführung der tuberkulostatischen Pharmaka in den 1940er-Jahren waren Morbidität wie Mortalität hoch. Inzwischen erzielen Mehrfach-Kombinationstherapien gute Heilungsraten und ermöglichen ein direktes chirurgisches Débridement ohne Komplikationen. Der Einsatz von Tuberkulostatika hat die Mortalität um 72,5% verringert, und chirurgische Interventionen bleiben ausgewählten klinischen Konstellationen vorbehalten.Keywords
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