Synthesis, characterization, and biological properties of Ni(II), Co(II), and Cu(II) complexes of Schiff bases derived from 4-aminobenzylamine
- 10 November 2009
- journal article
- research article
- Published by Taylor & Francis Ltd in Journal of Coordination Chemistry
- Vol. 62 (21), 3544-3551
- https://doi.org/10.1080/00958970903082192
Abstract
New Schiff bases, N,N′-bis(salicylidene)-4-aminobenzylamine (H2L1), N,N′-bis(3-methoxysalicylidene)-4-aminobenzylamine (H2L2), and N,N′-bis(4-hydroxysalicylidene)-4-aminobenzylamine (H2L3), with their nickel(II), cobalt(II), and copper(II) complexes have been synthesized and characterized by elemental analyses, electronic absorption, FT-IR, magnetic susceptibility, and conductance measurements. For the ligands, 1H and 13C NMR and mass spectra were obtained. The tetradentate ligands coordinate to the metal ions through the phenolic oxygen and azomethine nitrogens. The keto-enol tautomeric forms of the Schiff bases H2L1, H2L2, and H2L3 have been investigated in polar and apolar solvents. All compounds were non-electrolytes in DMSO (∼10−3 M) according to the conductance measurements. Antimicrobial activities of the Schiff bases and their complexes have been tested against Acinobacter baumannii, Pseudomonas aeruginosa, Micrococcus luteus, Bacillus megaterium, Corynebacterium xerosis, Staphylococcus aureus, Escherichia coli, Candida albicans, Rhodotorula rubra, and Kluyveromyces marxianus by the disc diffusion method; biological activity increases on complexation.Keywords
This publication has 25 references indexed in Scilit:
- Cd(II) and Cu(II) complexes of polydentate Schiff base ligands: synthesis, characterization, properties and biological activityInorganica Chimica Acta, 2005
- Antimicrobial activity studies of the binuclear metal complexes derived from tridentate Schiff base ligandsTransition Metal Chemistry, 1999
- pKa of the Protonated Schiff Base and Aspartic 85 in the Bacteriorhodopsin Binding Site Is Controlled by a Specific Geometry between the Two ResiduesBiochemistry, 1995
- Studies of Ti(IV) and Zr(IV) chelates with N2O2; Schiff bases of 2-hydroxy-1-naphthaldehyde with aromatic diaminesThermochimica Acta, 1989
- Alteration of pKa of the bacteriorhodopsin protonated Schiff base. A study with model compoundsBiochemistry, 1986
- Synthesis and characterization of copper(II) and nickel(II) complexes of the Schiff base derived from 2-(2-aminophenyl)benzimidazole and salicylaldehydeTransition Metal Chemistry, 1985
- The non-template synthesis of novel non-symmetrical, tetradentate Schiff bases. Their nickel(II) and cobalt(III) complexesInorganica Chimica Acta, 1982
- Electrochemical study of some cobalt schiff base complexes and their methyl derivatives. Relation to the behaviour of the cobalt-carbon bondTransition Metal Chemistry, 1982
- Substituted salen and baen tetradentate Schiff-base ligands. Synthesis, characterization, and electrochemistry of cobalt(III) complexesInorganic Chemistry, 1978
- The CN stretching frequency in the infrared spectra of Schiff's base complexes—I. Copper complexes of salicylidene anilinesSpectrochimica Acta Part A: Molecular Spectroscopy, 1967