Reservoir Competence of Various Rodents for the Lyme Disease Spirochete Borrelia spielmanii
- 1 June 2011
- journal article
- Published by American Society for Microbiology in Applied and Environmental Microbiology
- Vol. 77 (11), 3565-3570
- https://doi.org/10.1128/aem.00022-11
Abstract
To determine whether the pathogenic Lyme disease spirochete Borrelia spielmanii is adapted exclusively to garden dormice, we compared the reservoir competence of various rodent species for this spirochete, including sympatric and peridomestic rodents. The different kinds of rodents varied in their attractiveness to nymphal ticks and their level of susceptibility to tick-borne B. spielmanii infection, but only the edible dormouse appeared to be refractory. Although hazel dormice and Norway rats became infectious to ticks somewhat later than did garden dormice, they remained infectious for a longer period of time. During the course of a tick season, garden and hazel dormice contributed theoretically more than twice as many B. spielmanii -infected ticks than the somewhat less susceptible Norway rats and wood or yellow-necked mice. Hazel dormice appeared to be extraordinarily competent as reservoir hosts for B. spielmanii . Because peridomestic rodents proved to be reservoir competent, urban foci of transmission of B. spielmanii may affect the health of townspeople.Keywords
This publication has 27 references indexed in Scilit:
- Establishment of a minor groove binder-probe based quantitative real time PCR to detect Borrelia burgdorferi sensu lato and differentiation of Borrelia spielmanii by ospA-specific conventional PCRParasites & Vectors, 2010
- Human PathogenicBorrelia spielmaniisp. nov. Resists Complement-Mediated Killing by Direct Binding of Immune Regulators Factor H and Factor H-Like Protein 1Infection and Immunity, 2007
- Phylogenetic relationships and divergence times among dormice (Rodentia, Gliridae) based on three nuclear genesZoologica Scripta, 2007
- The role of fat dormouse (Glis glis L.) as reservoir host for spirochete Borrelia burgdorferi sensu lato in the region of Gorski Kotar, CroatiaEuropean Journal of Wildlife Research, 2007
- Epidemiological aspects and molecular characterization of Borrelia burgdorferi s.l. from southern Germany with special respect to the new species Borrelia spielmanii sp. nov.International Journal of Medical Microbiology, 2007
- Lyme Borreliosis andBorrelia spielmaniiEmerging Infectious Diseases, 2006
- Perpetuation of the Lyme Disease Spirochete Borrelia lusitaniae by LizardsApplied and Environmental Microbiology, 2006
- Adaptation of Diverse Lyme Disease Spirochetes in a Natural Rodent Reservoir HostInfection and Immunity, 2004
- Molecular systematics of dormice (Rodentia: Gliridae) and the radiation of Graphiurus in AfricaProceedings Of The Royal Society B-Biological Sciences, 2003
- An ospA-polymerase chain reaction/restriction fragment length polymorphism-based method for sensitive detection and reliable differentiation of all European Borrelia burgdorferi sensu lato species and OspA typesMedical Microbiology and Immunology, 2003