Glioma localization and excision using direct electrical stimulation for language mapping during awake surgery
- 16 March 2015
- journal article
- Published by Spandidos Publications in Experimental and Therapeutic Medicine
- Vol. 9 (5), 1962-1966
- https://doi.org/10.3892/etm.2015.2359
Abstract
The aim of this study was to investigate the method and significance of the application of direct electrical stimulation (DES) to the brain mapping of language functions during glioma surgery. A retrospective analysis of clinical data was performed for 91 cases of brain functional area glioma surgery under DES from January 2003 until January 2012. Following cortical electrical stimulation, 88 patients exhibited seizures involving facial or hand movements and 91 cases experienced language disorders such as counting interruption, naming errors or anomia. The most commonly observed areas of counting interruption were distributed on the posterior part of the left anterior central gyrus (47.7%), the operculum of the left inferior frontal gyrus (24.4%) and the triangular part of the left inferior frontal gyrus (12.8%). Postoperative magnetic resonance imaging demonstrated that overall excision was achieved in 53 cases and sub‑overall excision was performed in 31 cases. A total of 42 cases (46.2%) exhibited no postoperative neurological dysfunction, 39 cases (42.9%) exhibited brief language dysfunction, 27 cases (29.7%) experienced brief limb movement disorder, and one case appeared to have permanent neurological dysfunction. DES was indicated to be a reliable and noninvasive method for the intraoperative positioning of language areas, and was able to resect gliomas in the language area with maximal safety.Keywords
This publication has 37 references indexed in Scilit:
- A new philosophy in surgery for diffuse low-grade glioma (DLGG): Oncological and functional outcomesNeurochirurgie, 2013
- Subcortical surgical anatomy of the lateral frontal region: human white matter dissection and correlations with functional insights provided by intraoperative direct brain stimulationJournal of Neurosurgery, 2012
- Intraoperative subcortical electrical mapping of optic radiations in awake surgery for glioma involving visual pathwaysJournal of Neurosurgery, 2012
- Cognition and resective surgery for diffuse infiltrative glioma: an overviewJournal of Neuro-Oncology, 2012
- Awake surgery for incidental WHO grade II gliomas involving eloquent areasActa Neurochirurgica, 2011
- Awake Craniotomy vs Surgery Under General Anesthesia for Resection of Supratentorial LesionsNeurosurgery, 2011
- What Makes Surgical Tumor Resection Feasible in Broca's Area? Insights Into Intraoperative Brain MappingNeurosurgery, 2010
- Movement Intention After Parietal Cortex Stimulation in HumansScience, 2009
- Intraoperative mapping of language functions: a longitudinal neurolinguistic analysisJournal of Neurosurgery, 2008
- Lesions in Eloquent CortexNeurosurgery, 1997