Cell based screening of inhibitors of transthyretin aggregation
- 29 September 2006
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 348 (3), 889-897
- https://doi.org/10.1016/j.bbrc.2006.07.109
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Neutralization of Transthyretin Reverses the Neuroprotective Effects of Secreted Amyloid Precursor Protein (APP) in APPSwMice Resulting in Tau Phosphorylation and Loss of Hippocampal Neurons: Support for the Amyloid HypothesisJournal of Neuroscience, 2004
- Native state stabilization by NSAIDs inhibits transthyretin amyloidogenesis from the most common familial disease variantsLaboratory Investigation, 2004
- Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue cultureProceedings of the National Academy of Sciences of the United States of America, 2004
- Transthyretin is involved in depression‐like behaviour and exploratory activityJournal of Neurochemistry, 2004
- The systemic amyloidosesCurrent Opinion in Rheumatology, 2004
- Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of AmyloidogenesisJournal of Medicinal Chemistry, 2003
- Deposition of Transthyretin in Early Stages of Familial Amyloidotic PolyneuropathyThe American Journal of Pathology, 2001
- An Engineered Transthyretin Monomer that Is Nonamyloidogenic, Unless It Is Partially DenaturedBiochemistry, 2001
- Interaction of the Receptor for Advanced Glycation End Products (RAGE) with Transthyretin Triggers Nuclear Transcription Factor kB (NF-kB) ActivationLaboratory Investigation, 2000
- Discovering transthyretin amyloid fibril inhibitors by limited screeningBioorganic & Medicinal Chemistry, 1998