Multiresidue Determination of Pesticides in Malt Beverages by Capillary Gas Chromatography with Mass Spectrometry and Selected Ion Monitoring
- 18 September 2004
- journal article
- Published by American Chemical Society (ACS) in Journal of Agricultural and Food Chemistry
- Vol. 52 (21), 6361-6372
- https://doi.org/10.1021/jf040109g
Abstract
A method was developed to determine pesticides in malt beverages using solid phase extraction on a polymeric cartridge and sample cleanup with a MgSO4-topped aminopropyl cartridge, followed by capillary gas chromatography with electron impact mass spectrometry in the selected ion monitoring mode [GC-MS(SIM)]. Three GC injections were required to analyze and identify organophosphate, organohalogen, and organonitrogen pesticides. The pesticides were identified by the retention times of peaks of the target ion and qualifier-to-target ion ratios. GC detection limits for most of the pesticides were 5−10 ng/mL, and linearity was determined from 50 to 5000 ng/mL. Fortification studies were performed at 10 ng/mL for three malt beverages that differ in properties such as alcohol content, solids, and appearance. The recoveries from the three malt beverages were greater than 70% for 85 of the 142 pesticides (including isomers) studied. The data showed that the different malt beverage matrixes had no significant effect on the recoveries. This method was then applied to the screening and analysis of malt beverages for pesticides, resulting in the detection of the insectide carbaryl and the fungicide dimethomorph in real samples. The study indicates that pesticide levels in malt beverages are significantly lower than the tolerance levels set by the United States Environmental Protection Agency for malt beverage starting ingredients. The use of the extraction/cleanup procedure and analysis by GC-MS(SIM) proved effective in screening malt beverages for a wide variety of pesticides. Keywords: Beer; malt beverages; gas chromatography−mass spectrometry (GC-MS); selected ion monitoring (SIM); solid phase extraction; pesticidesKeywords
This publication has 14 references indexed in Scilit:
- Matrix effect in gas chromatographic determination of insecticides and fungicides in vegetablesInternational Journal of Environmental Analytical Chemistry, 2004
- Method Development and Fate Determination of Pesticide-Treated Hops and Their Subsequent Usage in the Production of BeerJournal of Agricultural and Food Chemistry, 2002
- Analysis of Carbamate Pesticides and Their Metabolites in Water by Solid Phase Extraction and Liquid Chromatography: A ReviewCritical Reviews in Analytical Chemistry, 2001
- Does further clean-up reduce the matrix enhancement effect in gas chromatographic analysis of pesticide residues in food?Journal of Chromatography A, 2000
- Matrix-induced effects: a critical point in the gas chromatographic analysis of pesticide residuesJournal of Chromatography A, 1998
- Matrix‐induced peak enhancement of pesticides in gas chromatogrtaphy: Is there a solution?Journal of High Resolution Chromatography, 1997
- Behavior of [14C]Atrazine, [14C]Terbutylazine, and Their Major Metabolites in the Brewing ProcessJournal of Agricultural and Food Chemistry, 1997
- A study of single compound additives to minimize the matrix induced chromatographic response enhancement observed in the gas chromatography of pesticide residuesJournal of High Resolution Chromatography, 1993
- Explanation of the matrix-induced chromatographic response enhancement of organophosphorus pesticides during open tubular column gas chromatography with splitless or hot on-column injection and flame photometric detectionJournal of Chromatography A, 1993
- Fate of ethylenebis(dithiocarbamates) and their metabolites during the brewing processJournal of Agricultural and Food Chemistry, 1984