The Cellular Basis of Hearing: The Biophysics of Hair Cells
- 15 November 1985
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 230 (4727), 745-752
- https://doi.org/10.1126/science.2414845
Abstract
A crucial event in the hearing process is the transduction of mechanical stimuli into electrical signals by hair cells, the sensory receptors of the internal ear. Stimulation results in the rapid opening of ionic channels in the mechanically sensitive organelles of these cells, their hair bundles. These transduction channels, which are nonselectively permeable, are directly excited by hair-bundle displacement. Hair cells are selectively responsive to particular frequencies of stimulation, both due to the mechanical properties of their hair bundles and because of an ensemble of ionic channels that constitute an electrical resonator.Keywords
This publication has 43 references indexed in Scilit:
- Quantum Noise and the Threshold of HearingPhysical Review Letters, 1985
- Voltage- and ion-dependent conductances in solitary vertebrate hair cellsNature, 1983
- Frequency tuning in a frog vestibular organNature, 1983
- Actin filaments, stereocilia, and hair cells of the bird cochlea. I. Length, number, width, and distribution of stereocilia of each hair cell are related to the position of the hair cell on the cochlea.The Journal of cell biology, 1983
- DIRECTIONAL SENSITIVITY OF INDIVIDUAL VERTEBRATE HAIR CELLS TO CONTROLLED DEFLECTION OF THEIR HAIR BUNDLES*Annals of the New York Academy of Sciences, 1981
- Actin in the inner ear: the remarkable structure of the stereociliumNature, 1980
- Further scanning electron microscope studies of lizard auditory papillaeJournal of Morphology, 1978
- Cochlear Anatomy of the Alligator LizardBrain, Behavior and Evolution, 1974
- The Minimum Perceptible Angular Acceleration Under Various ConditionsActa Oto-Laryngologica, 1949
- Brownian movement and hearingPhysica, 1948