Diagnostic management of clinically suspected acute deep vein thrombosis
- 27 July 2009
- journal article
- review article
- Published by Wiley in British Journal of Haematology
- Vol. 146 (4), 347-360
- https://doi.org/10.1111/j.1365-2141.2009.07732.x
Abstract
Deep vein thrombosis (DVT) is a common disease that may lead to potentially fatal complications, such as pulmonary embolism. In the past decades several diagnostic tools and algorithms for DVT have been studied. Currently the combination of a clinical decision rule, D-dimer testing and compression ultrasonography has proved to be safe and effective for the diagnosis of DVT in the lower extremities. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) can be useful as additional or secondary imaging modalities. This review will discuss the elements currently used in making the clinical diagnosis of DVT. These elements include clinical decision rules and D-dimer testing, different imaging investigations and the appropriate use of these within diagnostic algorithms in patients with clinically suspected DVT. Although current knowledge of the options available to diagnose DVT of the lower extremities is well established, there are still unresolved issues, including the optimal diagnosis of recurrent DVT and distal DVT. Furthermore, the diagnosis of DVT of the upper extremities will be discussed, including the different imaging modalities and the limitations of these techniques.Keywords
This publication has 70 references indexed in Scilit:
- Serial 2-Point Ultrasonography Plus D-Dimer vs Whole-Leg Color-Coded Doppler Ultrasonography for Diagnosing Suspected Symptomatic Deep Vein ThrombosisJAMA, 2008
- Aging of Acute Deep Vein Thrombosis Measured by Radiolabeled 99mTc-rt-PAJournal of Nuclear Medicine, 2007
- Diagnostic value of D-dimer in outpatients with suspected deep venous thrombosis receiving oral anticoagulationBlood Coagulation & Fibrinolysis, 2007
- Diagnosis and management of deep vein thrombosis of the upper extremity: a reviewEuropean Radiology, 2004
- Deep vein thrombosis of the upper extremity: intra- and interobserver study of digital subtraction venographyEuropean Radiology, 2003
- Prospective Study of Color Duplex Ultrasonography Compared with Contrast Venography in Patients Suspected of Having Deep Venous Thrombosis of the Upper ExtremitiesAnnals of Internal Medicine, 2002
- D-dimer testing as an adjunct to ultrasonography in patients with clinically suspected deep vein thrombosis: prospective cohort studyBMJ, 1998
- Comparison of colour Doppler ultrasound with venography in the diagnosis of axillary and subclavian vein thrombosisThe British Journal of Radiology, 1991
- Evaluation of Doppler examination for diagnosis of catheter-related deep vein thrombosisIntensive Care Medicine, 1989
- THROMBOTIC SIDE-EFFECTS OF LOWER-LIMB PHLEBOGRAPHYThe Lancet, 1976