Apolipoprotein A-I, A-II and C-II in black and white residents of Evans County.
- 1 August 1980
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 62 (2), 249-254
- https://doi.org/10.1161/01.cir.62.2.249
Abstract
Plasma levels of lipids, lipoprotein-cholesterol and three major apolipoproteins (ApoA-I, A-II and C-II) were studied in 318 black and white males and females randomly sampled in Evans County, Georgia. Black-white differences in lipid and lipoprotein-cholesterol concentrations were observed, with low-density fractions higher in whites and high-density fractions higher in blacks. Plasma levels of ApoA-I but not ApoA-II were higher in blacks than in whites and in females than in males. ApoC-II concentrations were lower in black than in white men and women. Black-white differences in atherogenic lipoprotein fractions were statistically explained (in the sense of association, not necessarily of causal process) by the differences in ApoC-II concentrations between the race groups. Black-white differences in anti etherogenic high-density lipoprotein-cholesterol were greater than statistically predicted by differences in ApoA lipoprotein levels. The findings are indicative of black-white differences in lipoprotein composition.This publication has 36 references indexed in Scilit:
- HIGH-DENSITY LIPOPROTEIN AND CORONARY RISK FACTORS IN NORMAL MENThe Lancet, 1979
- Serum High-Density-Lipoprotein Cholesterol in Women Using Oral Contraceptives, Estrogens and ProgestinsNew England Journal of Medicine, 1978
- Hypertriglyceridemia Associated with Deficiency of Apolipoprotein C-IINew England Journal of Medicine, 1978
- Alterations of lipid metabolism in healthy volunteers during long‐term ethanol intakeEuropean Journal of Clinical Investigation, 1977
- Serum lipoprotein profile in children from a biracial community: the Bogalusa Heart Study.Circulation, 1976
- Studies in Asymptomatic Primary HyperlipidaemiaActa Medica Scandinavica, 1975
- PLASMA-HIGH-DENSITY-LIPOPROTEIN CONCENTRATION AND DEVELOPMENT OF ISCHÆMIC HEART-DISEASEThe Lancet, 1975
- Effect of exercise and physical fitness on serum lipids and lipoproteinsAtherosclerosis, 1974
- Accelerated Triglyceride Secretion A METABOLIC CONSEQUENCE OF OBESITYJCI Insight, 1973
- 3. EFFECTS ON PARAMETERS OF LIVER FUNCTION, PLASMA LIPID CONCENTRATIONS AND LIPOPROTEIN PATTERNSActa Medica Scandinavica, 1973