Frailty and risk of mortality and hospitalization in nursing home residents affected by COVID-19
Open Access
- 19 February 2021
- journal article
- Published by PAGEPress Publications in Geriatric Care
- Vol. 7 (1)
- https://doi.org/10.4081/gc.2021.9635
Abstract
Coronavirus disease 2019 (COVID-19) is a widespread condition in nursing homes (NHs). However, no research was made regarding frailty in NH residents during COVID-19 pandemic. The aim of this study was to assess whether frailty, assessed by the multidimensional prognostic index (MPI), can predict mortality/hospitalization in COVID-19 NH residents. A Cox’s regression analysis was used, reporting the results as hazard ratios (HRs) with 95% confidence intervals (CIs). 1146 NH residents affected by COVID-19 were included (mean age: 86 years; 75.4% females). During the followup period, we observed 286 deaths and 239 hospitalizations. Taking those with MPI <0.41 as reference, an MPI ≥0.50 was associated with a higher risk of death (HR=1.41; 95%CI: 1.07-1.85). Similar results were obtained using the MPI score increase in 0.10 points (HR=1.12; 95%CI: 1.03-1.23). Using hospitalization as outcome, only MPI score as continuous variable was associated with this outcome (HR=1.08; 95%CI: 1.002-1.17). In conclusion, frailty, as assessed by the MPI, was associated with a significant higher risk of mortality and hospitalization in NH residents affected by COVID-19 further indicating the necessity of assessing frailty in NH.Keywords
This publication has 23 references indexed in Scilit:
- WHO must prioritise the needs of older people in its response to the covid-19 pandemicBMJ, 2020
- A multidimensional approach to frailty in older peopleAgeing Research Reviews, 2020
- Updated rapid risk assessment from ECDC on the novel coronavirus disease 2019 (COVID-19) pandemic: increased transmission in the EU/EEA and the UKEurosurveillance, 2020
- Using the Multidimensional Prognostic Index to Predict Clinical Outcomes of Hospitalized Older Persons: A Prospective, Multicenter, International StudyThe Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 2018
- Development and Validation of a Multidimensional Prognostic Index for Mortality Based on a Standardized Multidimensional Assessment Schedule (MPI-SVaMA) in Community-Dwelling Older SubjectsJournal of the American Medical Directors Association, 2013
- Daily Medication Use in Nursing Home Residents with Advanced DementiaJournal of the American Geriatrics Society, 2010
- Development and Validation of a Multidimensional Prognostic Index for One-Year Mortality from Comprehensive Geriatric Assessment in Hospitalized Older PatientsRejuvenation Research, 2008
- Inappropriate Hospitalization of Nursing Facility Residents: A Symptom of a Sick System of Care for Frail Older PeopleJournal of the American Geriatrics Society, 2000
- Constructing Prediction Trees from Data: The RECPAM ApproachPublished by Springer Science and Business Media LLC ,1993
- A Short Portable Mental Status Questionnaire for the Assessment of Organic Brain Deficit in Elderly Patients†Journal of the American Geriatrics Society, 1975