Prevalence of serological markers of hepatitis B virus in pregnant women from Paraná State, Brazil.
Open Access
- 1 August 2006
- journal article
- Published by FapUNIFESP (SciELO) in Brazilian Journal of Medical and Biological Research
- Vol. 39 (8), 1083-1090
- https://doi.org/10.1590/s0100-879x2006000800011
Abstract
The prevalence of hepatitis B virus (HBV) in Brazil increases from South to North but moderate to elevated prevalence has been detected in the Southwest of Paraná State. The prevalence of serological markers of HBV was evaluated in 3188 pregnant women from different counties in Paraná State and relevant epidemiological features were described. The prevalence of HBV markers in pregnant women for the state as a whole was 18.5% (95% CI = 17.2-19.9), ranging from 7.2% in Curitiba to 38.5% in Francisco Beltrão. The endemicity of HBV marker prevalence in pregnant women was intermediate in Cascavel, Foz do Iguaçu, and Francisco Beltrão, and low in Curitiba, Londrina, Maringá, and Paranaguá. Multiple logistic regression showed that HBV marker prevalence increased with age, was higher among black women, among women of Italian and German descent, and among women who had family members in neighboring Rio Grande do Sul State. Univariate analysis showed that HBV marker prevalence was also higher among women with no education or only primary education, with a lower family income and whose families originated from the South Region of Brazil. Pregnant women not having positive HBV markers (anti-HBc, HBsAg or anti-HBs detected by ELISA) corresponded to 73.7% of the population studied, implying that HBV vaccination needs to be reinforced in Paraná State. The highest prevalence was found in three counties that received the largest number of families from Santa Catarina and Rio Grande do Sul, where most immigrants were of German or Italian ascendance. This finding probably indicates that immigrants that came to this area brought HBV infection to Southwestern Paraná State.Keywords
This publication has 14 references indexed in Scilit:
- Incidence and Risk Factors for Acute Hepatitis B in the United States, 1982–1998: Implications for Vaccination ProgramsThe Journal of Infectious Diseases, 2002
- Marcadores sorológicos de hepatite B em indivíduos submetidos a exames de sangue em unidades de saúdeRevista de Saúde Pública, 2000
- Soroprevalência para hepatite A e hepatite B em quatro centros no BrasilRevista da Sociedade Brasileira de Medicina Tropical, 2000
- Outbreak of hepatitis B virus in recent arrivals to the Brazilian AmazonJournal of Medical Virology, 1998
- Soroepidemiologia para o virus da hepatite B (VHB) em gestantes/parturientes e sua transmissão para recém-nascidos em Goiânia, GORevista da Sociedade Brasileira de Medicina Tropical, 1996
- Global programme for control of hepatitis B infectionVaccine, 1995
- Hepatitis B and C prevalences among blood donors in the south region of BrazilMemórias do Instituto Oswaldo Cruz, 1994
- Immunization aganist hepatitis B in children from endemic zone: evaluation of the antibody response against the DNA recombinant vaccine (Engerix B-20 mcg)Revista do Instituto de Medicina Tropical de São Paulo, 1993
- Hepatitis B: Evolving Epidemiology and Implications for ControlSeminars in Liver Disease, 1991
- Hepatitis B: global importance and need for controlVaccine, 1990