Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Abstract

Non-small-cell lung cancer (NSCLC) accounts for 80%–85% of all lung cancer cases. Approximately 90% of lung cancers among men and 80% among women are related to smoking. The majority of patients present with advanced disease. The incidence differs considerably across different countries in Europe. The rates vary from 22 to 63 per 100 000 and from 5 to 33/100 000 per year in men and women, respectively. In most European countries, the incidence continues to rise in women but decreases in men. This trend seems to occur later in Southern and Eastern Europe than in the Northern regions.