Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER
Open Access
- 1 May 2003
- journal article
- Published by Elsevier BV in Journal of Lipid Research
- Vol. 44 (5), 978-985
- https://doi.org/10.1194/jlr.m300020-jlr200
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trialThe Lancet, 2002
- Co-translational Interactions of Apoprotein B with the Ribosome and Translocon during Lipoprotein Assembly or Targeting to the ProteasomePublished by Elsevier BV ,2001
- The Amino-terminal Domain of Apolipoprotein B Does Not Undergo Retrograde Translocation from the Endoplasmic Reticulum to the CytosolPublished by Elsevier BV ,2000
- Decreased Secretion of ApoB Follows Inhibition of ApoB−MTP Binding by a Novel AntagonistBiochemistry, 2000
- The role of the LDL receptor in apolipoprotein B secretionJCI Insight, 2000
- Translocation Efficiency, Susceptibility to Proteasomal Degradation, and Lipid Responsiveness of Apolipoprotein B Are Determined by the Presence of β Sheet DomainsPublished by Elsevier BV ,1998
- Microsomal triglyceride transfer proteinBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1997
- Ubiquitin-Proteasome Pathway Mediates Intracellular Degradation of Apolipoprotein BBiochemistry, 1996
- Lovastatin therapy in receptor-negative homozygous familial hypercholesterolemia: Lack of effect on low-density lipoprotein concentrations or turnoverThe Journal of Pediatrics, 1988
- Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial HypercholesterolemiaNew England Journal of Medicine, 1984