How may stressful experiences contribute to the development of temporomandibular disorders?
- 22 August 2006
- journal article
- review article
- Published by Springer Science and Business Media LLC in Clinical Oral Investigations
- Vol. 10 (4), 261-268
- https://doi.org/10.1007/s00784-006-0064-1
Abstract
Temporomandibular disorders (TMD) comprise the most common cause of chronic facial pain conditions, and they are often associated with somatic and psychological complaints including fatigue, sleep disturbances, anxiety, and depression. For many health professionals, the subjectivity of pain experience is frequently neglected even when the clinic does not find any plausible biologic explanation for the pain. This strictly biomedical vision of pain cannot be justified scientifically. The purpose of this study is to demonstrate, by original articles from the literature and recent studies conducted in our own laboratory, the biological processes by which psychological stress can be translated into the sensation of pain and contribute to the development of TMD. The role of the hypothalamic–pituitary–adrenal axis, the serotoninergic and opioid systems in the pathogenesis of facial pain is exposed, including possible future therapeutic approaches. It is hoped that knowledge from apparently disparate fields of dentistry, integrated into a multidisciplinary clinical approach to TMD, will improve diagnosis and treatment for this condition through a clinical practice supported by scientific knowledge.Keywords
This publication has 93 references indexed in Scilit:
- Effects of ethanol on deep pain evoked by formalin injected in TMJ of ratLife Sciences, 2003
- Descending control of painProgress in Neurobiology, 2002
- Neurocircuitry of stress: central control of the hypothalamo–pituitary–adrenocortical axisTrends in Neurosciences, 1997
- Comorbidity of depression with chronic facial pain and temporomandibular disordersOral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 1996
- Psychoneuroimmunology: The interface between behavior, brain, and immunity.American Psychologist, 1994
- Psychoneuroimmunology: The interface between behavior, brain, and immunity.American Psychologist, 1994
- Facial pain, distress, and immune functionBrain, Behavior, and Immunity, 1990
- Effects of Fenfluramine and Ritanserin on Prolactin Response to Insulin-Induced Hypoglycemia in Obese Patients: Evidence for Failure of the Serotoninergic SystemHormone Research, 1989
- An investigation of the stress factor in the mandibular dysfunction syndromeJournal of Dentistry, 1985
- Oral behavioral patterns in facial pain, headache and non-headache populationsBehaviour Research and Therapy, 1983