Alzheimer's Disease, Trisomy 21, and Myeloproliferative Disorders: Associations Suggesting a Genetic Diathesis
- 15 April 1977
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 196 (4287), 322-323
- https://doi.org/10.1126/science.196.4287.322
Abstract
Relatives of probands with Alzheimer's disease had excessive incidences of trisomy 21 and myeloproliferative disorders. Microtubules are structures that are likely to be affected by a genetic defect causing a predisposition to Alzheimer's disease, trisomy 21 and, possibly, to myeloproliferative disorders.Keywords
This publication has 10 references indexed in Scilit:
- The Genetics of Alzheimer's DiseaseArchives of General Psychiatry, 1977
- Neurofibrillary tangles of paired helical filamentsJournal of the Neurological Sciences, 1976
- What moves chromosomes, microtubules or microfilaments?Biosystems, 1975
- Alzheimer Degeneration in Down SyndromeArchives of Neurology, 1975
- STUDIES ON THE MECHANISM OF MITOSISAnnals of the New York Academy of Sciences, 1975
- Presenile dementia in Down's syndromeNeurology, 1974
- NEUROFIBRILLARY PATHOLOGYJournal of Neuropathology and Experimental Neurology, 1970
- An epidemiological study of childhood leukemiaJournal of Chronic Diseases, 1965
- MONGOLISM*British Medical Bulletin, 1961
- Simultaneous Occurrence of Mongolism and LeukemiaA.M.A. Journal of Diseases of Children, 1957