HDAC6 inhibition induces glioma stem cells differentiation and enhances cellular radiation sensitivity through the SHH/Gli1 signaling pathway
- 6 December 2017
- journal article
- research article
- Published by Elsevier BV in Cancer Letters
- Vol. 415, 164-176
- https://doi.org/10.1016/j.canlet.2017.12.005
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (31570851, 81201742)
- Priority Academic Program Development of Jiangsu Higher Education Institutions
This publication has 44 references indexed in Scilit:
- Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog–GLI pathwayMolecular and Cellular Biochemistry, 2012
- Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladderNature, 2011
- XIAP as a ubiquitin ligase in cellular signalingCell Death & Differentiation, 2009
- GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformationGenes & Development, 2009
- Hedgehog: functions and mechanismsGenes & Development, 2008
- Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem CellsCancer Cell, 2008
- Glioma stem cells promote radioresistance by preferential activation of the DNA damage responseNature, 2006
- Vertebrate Smoothened functions at the primary ciliumNature, 2005
- Hedgehog signalling in the mouse requires intraflagellar transport proteinsNature, 2003
- IAP proteins: blocking the road to death's doorNature Reviews Molecular Cell Biology, 2002