Psychiatric Symptoms in Children and Adolescents With Cyclic Vomiting Syndrome and their Parents
- 13 December 2007
- journal article
- research article
- Published by Wiley in Headache: The Journal of Head and Face Pain
- Vol. 48 (2), 259-266
- https://doi.org/10.1111/j.1526-4610.2007.00997.x
Abstract
Objective.— To conduct a pilot study to evaluate the prevalence of psychiatric symptoms in children and adolescents with cyclic vomiting syndrome and to assess family history of psychiatric disorder. Background.— Little is known about psychiatric comorbidity in youth with cyclic vomiting syndrome, a periodic syndrome. Methods.— Eighty-five parents, of children aged 3-18 years with cyclic vomiting syndrome confirmed in a multidisciplinary clinic, completed the age-appropriate Children's Symptom Inventory, a questionnaire that screens for psychiatric symptoms in pediatric patients. Twenty-one adolescents aged 13-18 years completed the Youth's Report, a self-report form of this questionnaire. Sixty-two parents completed a family psychiatric history checklist. Results.— These children and their parents evidenced a high prevalence of anxiety and mood symptoms compared to norms of the Children's Symptom Inventory and population norms for internalizing psychiatric disorders. On the age-appropriate Children's Symptom Inventory, 47% of subjects (40/85) met diagnostic cut-off for an anxiety disorder, and 14% (12/85) for an affective disorder. Discrepancies were found in parent and adolescent reports for symptoms of panic disorder (chi-square = 4.83, df = 1, P = .028), posttraumatic stress disorder (chi-square = 6.87, df = 1, P = .009), and somatization disorder (chi-square = 6.41, df = 1, P = .01), with parents reporting significantly more symptoms than the adolescents. Internalizing disorders were also prevalent in the parents with 59% (36/62) endorsing either an anxiety and/or an affective disorder. Mothers reported a significantly higher prevalence of anxiety disorders (35%) than did fathers (13%) (chi-square = 8.43, df = 1, P < .004). Conclusion.— Children and adolescents with cyclic vomiting syndrome appear to be at increased risk for internalizing psychiatric disorders, especially anxiety disorders. Further research using standardized psychiatric interviews and a control group are indicated to further assess psychiatric disorders in children and adolescents with cyclic vomiting syndrome.Keywords
This publication has 23 references indexed in Scilit:
- Headache and Psychological Functioning in Children and AdolescentsHeadache: The Journal of Head and Face Pain, 2006
- Relationship Between Cyclic Vomiting Syndrome and MigraineClinical Pediatrics, 2005
- Comorbidity of Psychiatric and Behavioral Disorders in Pediatric MigraineHeadache: The Journal of Head and Face Pain, 2005
- Maternal inheritance in cyclic vomiting syndromeAmerican Journal of Medical Genetics Part A, 2005
- Psychiatric Symptoms in Children With Primary HeadacheJournal of the American Academy of Child & Adolescent Psychiatry, 2004
- Further Evidence of Reliability and Validity of the Child Symptom Inventory-4: Parent Checklist in Clinically Referred BoysJournal of Clinical Child & Adolescent Psychology, 2002
- Is cyclic vomiting syndrome related to migraine?The Journal of Pediatrics, 1999
- Precipitants and aetiology of cyclic vomiting syndromeActa Paediatrica, 1998
- COMORBIDITY OF MIGRAINE AND PSYCHIATRIC DISORDERSNeurologic Clinics, 1997
- Diathesis-stress theories in the context of life stress research: Implications for the depressive disorders.Psychological Bulletin, 1991