Neuropsychological and behavioral functioning in children with and without obstructive sleep apnea referred for tonsillectomy
- 25 June 2008
- journal article
- research article
- Published by Cambridge University Press (CUP) in Journal of the International Neuropsychological Society
- Vol. 14 (4), 571-581
- https://doi.org/10.1017/s1355617708080776
Abstract
Adenotonsillectomy (AT) is among the most common pediatric surgical procedures and is performed as often for obstructive sleep apnea (OSA) as for recurrent tonsillitis. This study compared behavioral, cognitive, and sleep measures in 27 healthy control children recruited from a university hospital-based pediatric general surgery clinic with 40 children who had OSA (AT/OSA+) and 27 children who did not have OSA (AT/OSA−) scheduled for AT. Parental ratings of behavior, sleep problems, and snoring, along with specific cognitive measures (i.e., short-term attention, visuospatial problem solving, memory, arithmetic) reflected greater difficulties for AT children compared with controls. Differences between the AT/OSA− and control groups were larger and more consistent across test measures than were those between the AT/OSA+ and control groups. The fact that worse outcomes were not clearly demonstrated for the AT/OSA+ group compared with the other groups was not expected based on existing literature. This counterintuitive finding may reflect a combination of factors, including age, daytime sleepiness, features of sleep-disordered breathing too subtle to show on standard polysomnography, and academic or environmental factors not collected in this study. These results underscore the importance of applying more sophisticated methodologies to better understand the salient pathophysiology of childhood sleep-disordered breathing. (JINS, 2008,14, 571–581.)This publication has 56 references indexed in Scilit:
- Childhood Obstructive Sleep Apnea Associates with Neuropsychological Deficits and Neuronal Brain InjuryPLoS Medicine, 2006
- Sleep-Disordered Breathing, Behavior, and Cognition in Children Before and After AdenotonsillectomyPEDIATRICS, 2006
- Child Behavior after Adenotonsillectomy for Obstructive Sleep Apnea SyndromeThe Laryngoscope, 2005
- Neuropsychological and Psychosocial Function in Children with a History of Snoring or Behavioral Sleep ProblemsThe Journal of Pediatrics, 2005
- Hippocampal area metabolites relate to severity and cognitive function in obstructive sleep apneaSleep Medicine, 2004
- Sleep-disordered breathing symptoms are associated with poorer cognitive function in 5-year-old childrenThe Journal of Pediatrics, 2004
- Cognitive Executive Dysfunction in Children with Mild Sleep-Disordered BreathingBiological Research For Nursing, 2004
- Changes in brain morphology associated with obstructive sleep apneaSleep Medicine, 2003
- Sleep disordered breathing: Effects of adenotonsillectomy on behaviour and psychological functioningEuropean Journal of Pediatrics, 1996
- Cognitive and Task-Related EEG Correlates of Arithmetic Performance in AdolescentsJournal of Clinical and Experimental Neuropsychology, 1987