On the fixation probability of mutant genes in a subdivided population

Abstract

SUMMARY Following Moran's (1962) method, it was shown that the fixation probability of a mutant gene is not altered by the subdivision of a population into partially isolated colonies, if the following conditions are met; fitness is additive, samplings and selection is done separately in each colony, and migration between colonies does not change the gene frequency in the whole population. This conclusion was checked by simulation experiments.