The prevalence of the metabolic syndrome and type 2 diabetes mellitus in children and adolescents
Open Access
- 15 November 2004
- journal article
- research article
- Published by Springer Science and Business Media LLC in International Journal of Obesity
- Vol. 28 (S3), S70-S74
- https://doi.org/10.1038/sj.ijo.0802811
Abstract
OBJECTIVE: To review the prevalence of the metabolic syndrome and type 2 diabetes in children and adolescents. METHOD: Literature review. RESULTS: It is well demonstrated that cardiovascular risk factors are frequent in childhood obesity and they tend to cluster. However, the frequency of the metabolic syndrome in childhood and adolescence has been investigated only by few studies. In spite of the diverse criteria used for defining the metabolic syndrome, it is evident that the syndrome is already highly prevalent among obese children and adolescents. Population-based data suggest that the epidemic of pediatric obesity is being followed by an increase of type 2 diabetes mellitus, especially in the United States and in minorities. For the European countries, there are no population-based incidence and prevalence data concerning type 2 diabetes mellitus in children and adolescents. From the available data, the magnitude of the problem in the European Caucasian population seems to be much less than in North America. CONCLUSION: There is an urgent need to establish internationally acceptable criteria for the metabolic syndrome in children and adolescents and to commence screening for this syndrome. Although type 2 diabetes mellitus is still rare among European children, screening is recommended for type 2 diabetes mellitus or impaired glucose tolerance in children and especially in adolescents with substantial risk for the development of this disease.Keywords
This publication has 26 references indexed in Scilit:
- The Metabolic Syndrome in Overweight Hispanic Youth and the Role of Insulin SensitivityJournal of Clinical Endocrinology & Metabolism, 2004
- Health consequences of obesityArchives of Disease in Childhood, 2003
- Prevalence of a Metabolic Syndrome Phenotype in AdolescentsArchives of Pediatrics & Adolescent Medicine, 2003
- Waist circumference for the screening of the metabolic syndrome in childrenActa Paediatrica, 2002
- Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)JAMA, 2001
- Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO ConsultationDiabetic Medicine, 1998
- Association between Multiple Cardiovascular Risk Factors and Atherosclerosis in Children and Young AdultsNew England Journal of Medicine, 1998
- Insulin secretion and carbohydrate tolerance in childhood obesityKlinische Padiatrie, 1990
- Additive Hypoglycemic Effects of Drugs That Modify Free-Fatty Acid Metabolism by Different Mechanisms in Rats With Streptozocin-Induced DiabetesDiabetes, 1988
- Relationship between Obesity, Chemical Diabetes and Beta Pancreatic Function in ChildrenDiabetes, 1969