Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function
- 6 October 2011
- journal article
- research article
- Published by Elsevier BV in Neuron
- Vol. 72 (1), 72-85
- https://doi.org/10.1016/j.neuron.2011.08.022
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (1R01NS048276, R01 DA022202)
- March of Dimes Foundation (1-FY07-482, T32CA009361)
- Damon Runyon Cancer Research Foundation (1R21NS070250-01A1, DRG-2048-10, K08MH90306, K99 NS058391)
This publication has 42 references indexed in Scilit:
- The Role of MeCP2 in the BrainAnnual Review of Cell and Developmental Biology, 2011
- Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memoryNature Neuroscience, 2011
- A Tissue-Specific Atlas of Mouse Protein Phosphorylation and ExpressionCell, 2010
- Charting histone modifications and the functional organization of mammalian genomesNature Reviews Genetics, 2010
- Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin StateMolecular Cell, 2010
- MeCP2 Controls Excitatory Synaptic Strength by Regulating Glutamatergic Synapse NumberNeuron, 2007
- Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine MaturationNeuron, 2006
- Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett SyndromeProceedings of the National Academy of Sciences of the United States of America, 2005
- MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic ChromatinCell, 1997
- DNA Methylation Specifies Chromosomal Localization of MeCP2Molecular and Cellular Biology, 1996