Effect of Endovascular Treatment With Medical Management vs Standard Care on Severe Cerebral Venous Thrombosis

Abstract

Cerebral venous thrombosis (CVT) is a distinct cause of stroke that primarily affects young adult and middle-aged patients.^1,2 Approximately half of patients with CVT have an intracerebral hemorrhage (ICH) at presentation.³ All major guidelines recommend anticoagulation with heparin as the standard treatment for CVT^4,5 regardless of the presence of an ICH. Despite heparin treatment, however, approximately 20% of patients with CVT retain their disability or die.³ Baseline variables associated with an increased risk of poor outcome include mental status disorder, coma state, ICH, and thrombosis of the deep venous system.³