Oxycodone Pharmacokinetics and Pharmacodynamics in the Rat in the Presence of the P-Glycoprotein Inhibitor PSC833
- 1 May 2005
- journal article
- research article
- Published by Elsevier BV in Journal of Pharmaceutical Sciences
- Vol. 94 (5), 1060-1066
- https://doi.org/10.1002/jps.20327
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- The use of liquid chromatography/mass spectrometry for quantitative analysis of oxycodone, oxymorphone and noroxycodone in Ringer solution, rat plasma and rat brain tissueRapid Communications in Mass Spectrometry, 2004
- Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteersPharmacogenetics, 2003
- Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivoJCI Insight, 2002
- A new multidrug resistance protein at the blood–brain barrierBiochemical and Biophysical Research Communications, 2002
- Interindividual Variability of the Clinical Pharmacokinetics of MethadoneClinical Pharmacokinetics, 2002
- Uptake and efflux of the peptidic delta-opioid receptor agonist [D-penicillamine2,5]-enkephalin at the murine blood–brain barrier by in situ perfusionNeuroscience Letters, 2001
- HumanMDR1and Mousemdr1aP-Glycoprotein Alter the Cellular Retention and Disposition of Erythromycin, but Not of Retinoic Acid or Benzo(a)pyreneArchives of Biochemistry and Biophysics, 1998
- Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.JCI Insight, 1997
- Effect of the P-glycoprotein inhibitor, SDZ PSC 833, on the blood and brain pharmacokinetics of colchicineLife Sciences, 1997
- Antinociceptive Effects and Central Nervous System Depression Caused by Oxycodone and Morphine in RatsBasic & Clinical Pharmacology & Toxicology, 1992