Difference in the Incidence Trend of Nasopharyngeal and Oropharyngeal Carcinomas in Taiwan: Implication from Age-Period-Cohort Analysis
- 1 May 2006
- journal article
- Published by American Association for Cancer Research (AACR) in Cancer Epidemiology, Biomarkers & Prevention
- Vol. 15 (5), 856-861
- https://doi.org/10.1158/1055-9965.epi-05-0821
Abstract
Lifestyle factors are considered important for the pathogenesis of both nasopharyngeal and oropharyngeal carcinomas. In Taiwan, the incidence of nasopharyngeal carcinoma gradually decreased over the past 20 years, whereas that of oropharyngeal carcinoma increased rapidly. To compare the incidence trends of nasopharyngeal and oropharyngeal carcinomas in Taiwan, the age-period-cohort model was used to analyze epidemiologic data from 1981 to 2000 obtained from the Taiwan Cancer Registry. The calendar time period of 1986 to 1990 and the 1931 to 1940 birth cohort were used as reference groups for estimates of relative risk. For nasopharyngeal carcinoma, the incidence seemed to decrease in most age groups and was more prominent in women (30%) than in men (23%). For oropharyngeal carcinoma, the incidence increased in all age groups and was more prominent in men (391.4%) than in women (59.2%). Cohort effect was found for both nasopharyngeal and oropharyngeal carcinomas. The relative risk of nasopharyngeal carcinoma for the 1971 to 1980 birth cohort was 0.38 for women and 0.68 for men. The relative risk of oropharyngeal carcinoma for the 1971 to 1980 cohort was 45.67 for men and 2.69 for women. Change in lifestyle seemed to be an important factor for the difference in the incidence trend between nasopharyngeal and oropharyngeal carcinomas and between men and women. (Cancer Epidemiol Biomarkers Prev 2006;15(5):856–61)Keywords
This publication has 34 references indexed in Scilit:
- Significant Difference in the Trends of Female Breast Cancer Incidence Between Taiwanese and Caucasian Americans: Implications from Age-Period-Cohort AnalysisCancer Epidemiology, Biomarkers & Prevention, 2005
- Evaluation of Risk Factors for Nasopharyngeal Carcinoma in High-Risk Nasopharyngeal Carcinoma Families in TaiwanCancer Epidemiology, Biomarkers & Prevention, 2005
- Behavior and Cancer PreventionJournal of Clinical Oncology, 2005
- Changing epidemiology of nasopharyngeal carcinoma in Hong Kong over a 20‐year period (1980–99): An encouraging reduction in both incidence and mortalityInternational Journal of Cancer, 2002
- Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese populationXenobiotica, 2002
- Incidence and mortality from stomach cancer in Japan, Slovenia and the USAInternational Journal of Cancer, 2001
- Implications of Birth Cohort Patterns in Interpreting Trends in Breast Cancer RatesJNCI Journal of the National Cancer Institute, 1992
- Trends in female breast cancer in Connecticut and the United StatesJournal of Clinical Epidemiology, 1991
- The decline in the incidence of stomach cancer in sweden 1960‐1984: A birth cohort phenomenonInternational Journal of Cancer, 1991
- Models for temporal variation in cancer rates. II: Age–period–cohort modelsStatistics in Medicine, 1987