Ocular features of Behcet's disease: An international collaborative study
Open Access
- 16 November 2007
- journal article
- world view
- Published by BMJ in British Journal of Ophthalmology
- Vol. 91 (12), 1579-1582
- https://doi.org/10.1136/bjo.2007.123554
Abstract
Objective: To investigate the clinical features of ocular lesions in Behçet’s disease in different countries. Methods: A descriptive questionnaire survey was performed. Results: 25 eye centres in 14 countries returned questionnaires on prevalent cases in 2006. Clinical data were analysed on 1,465 patients with ocular lesions. Recurrent oral aphthous ulcers were reported in 94.5%, skin lesions in 69.5% and genital ulcers in 61.4%. Most of the patients had bilateral and recurrent intraocular inflammation. Poor visual acuity was seen in 18.9% in women, but 24.8% in men (pConclusions: We report the largest contemporary international case series of patients with ocular involvement in Behçet’s disease. Panuveitis was significantly more frequent in men than women, and men tended to have a worse visual prognosis. There were some differences in the clinical pattern of Behçet’s disease in different countries. Despite modern treatment, the disease still carries a poor visual prognosis with one-quarter of the patients blind.Keywords
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