Prolonged perioperative surgical prophylaxis within European hospitals: an exercise in uncertainty avoidance?
Open Access
- 13 November 2013
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 69 (4), 1142-1144
- https://doi.org/10.1093/jac/dkt461
Abstract
Socio-cultural factors have been hypothesized to be important drivers for inappropriate antibiotic prescribing in ambulatory care. This study sought to assess any potential role in perioperative surgical prophylaxis (PAP) administered for >24 h (PAP > 24). Within hospitals, PAP continues to be administered for longer than 24 h, despite unequivocal evidence of ineffectiveness beyond this period. A recently published European Centre for Disease Prevention and Control (ECDC) point prevalence survey (PPS) has reported that in 70% of participating countries, PAP > 24 was administered in more than half of the surgical operations surveyed. Correlation and simple linear regression modelling was performed using the PAP > 24 proportions for the countries in the ECDC PPS report and the respective scores for the cultural construct of uncertainty avoidance (UA), as detailed by Hofstede. Pearson correlation analysis produced a moderately strong coefficient (r) of 0.50 (95% CI 0.16–0.74; P = 0.007). Simple regression yielded a model of PAP > 24 = 29.87 + 0.40UA (R2 = 0.25; P = 0.007). Cultural factors, namely UA, appear to be an important driver for PAP > 24. Any strategy aimed at improving prolonged PAP should be informed by clear knowledge of local socio-cultural barriers, so as to achieve the most successful intervention possible.This publication has 7 references indexed in Scilit:
- Understanding the epidemiology of MRSA in Europe: do we need to think outside the box?Journal of Hospital Infection, 2012
- National cultural dimensions as drivers of inappropriate ambulatory care consumption of antibiotics in Europe and their relevance to awareness campaignsJournal of Antimicrobial Chemotherapy, 2011
- Preventing surgical site infectionsExpert Review of Anti-infective Therapy, 2010
- Are cultural dimensions relevant for explaining cross-national differences in antibiotic use in Europe?BMC Health Services Research, 2008
- Antimicrobial Resistance Determinants and Future ControlEmerging Infectious Diseases, 2005
- Practice Guidelines: Useful and "Participative" Method?Archives of Internal Medicine, 2001
- Prolonged Antibiotic Prophylaxis After Cardiovascular Surgery and Its Effect on Surgical Site Infections and Antimicrobial ResistanceCirculation, 2000