Vascular Pattern and Spectral Parameters of Power Doppler Ultrasound as Predictors of Malignancy Risk in Thyroid Nodules
- 1 December 2008
- journal article
- research article
- Published by Wiley in The Laryngoscope
- Vol. 118 (12), 2182-2186
- https://doi.org/10.1097/mlg.0b013e3181864ae7
Abstract
Introduction: Determination whether spectral Doppler ultrasound parameters, including resistance index (RI) and pulsatility index (PI), or vascular pattern can be used to distinguish malignant from benign thyroid nodules. Materials and Methods: We prospectively examined 85 thyroid nodules in patients undergoing surgery. The flow pattern seen via power Doppler examination was ranked for each nodule on a scale of 0 to 4 as follows: absent, perinodular alone, mixed with perinodular prominency, mixed with intranodular prominency, and exclusively intranodular, respectively. For each nodule, the RI and PI values were recorded as the average of the recordings obtained. Pathological examination were used as a proof of final diagnosis to categorize all nodules as benign or malignant. Results: The malignant nodules had a mean RI of 0.72 ± 0.13. These values were significantly higher than those associated with benign nodules (0.60 ± 0.08) (P = .000). Malignant nodules had a mean PI of 1.15 ± 0.33 that were also significantly different from those associated with benign nodules (0.91 ± 0.19) (P = .000). Shifting to intranodular vascularization had a significant correlation with malignancy (P = .001). Conclusion: Spectral parameter and vascular pattern are useful to distinguish malignant from benign thyroid nodules, especially for those with suspicious or undetermined fine-needle aspiration biopsy.Keywords
This publication has 16 references indexed in Scilit:
- Power Doppler US patterns of vascularity and spectral Doppler US parameters in predicting malignancy in thyroid nodulesClinical Radiology, 2007
- Management of Thyroid Nodules Detected at US: Society of Radiologists in Ultrasound Consensus Conference StatementRadiology, 2005
- Flow Pattern and Vascular Resistive Index as Predictors of Malignancy Risk in Thyroid Follicular NeoplasmsJournal of Ultrasound in Medicine, 2005
- Thyroid nodules: Evaluation with power Doppler and duplex Doppler ultrasoundOtolaryngology -- Head and Neck Surgery, 2005
- Common and Uncommon Sonographic Features of Papillary Thyroid CarcinomaJournal of Ultrasound in Medicine, 2003
- Can Color Doppler Sonography Aid in the Prediction of Malignancy of Thyroid Nodules?Journal of Ultrasound in Medicine, 2003
- Risk of Malignancy in Nonpalpable Thyroid Nodules: Predictive Value of Ultrasound and Color-Doppler FeaturesJournal of Clinical Endocrinology & Metabolism, 2002
- Imaging the thyroidClinical Radiology, 1998
- The role of colour and duplex Doppler ultrasound in the assessment of thyroid nodulesAustralasian Radiology, 1995
- Thyroid cancer in thyroid nodules: Finding a needle in the haystackAmerican Journal Of Medicine, 1992