Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling
Open Access
- 21 June 2007
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 21 (13), 3666-3676
- https://doi.org/10.1096/fj.07-8329com
Abstract
The blood-brain barrier (BBB) prevents the entrance of circulating molecules and immune cells into the central nervous system. The barrier is formed by specialized brain endothelial cells that are in...Keywords
This publication has 61 references indexed in Scilit:
- The Blood-Brain Barrier and Its Role in Immune Privilege in the Central Nervous SystemJournal of Neuropathology and Experimental Neurology, 2003
- Size-selective loosening of the blood-brain barrier in claudin-5–deficient miceThe Journal of cell biology, 2003
- Multiple domains of occludin are involved in the regulation of paracellular permeabilityJournal of Cellular Biochemistry, 2000
- Manner of Interaction of Heterogeneous Claudin Species within and between Tight Junction StrandsThe Journal of cell biology, 1999
- Occludin and claudins in tight-junction strands: leading or supporting players?Trends in Cell Biology, 1999
- The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin CytoskeletonJournal of Biological Chemistry, 1998
- Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to OccludinThe Journal of cell biology, 1998
- Cell signalling: MAGUK magicCurrent Biology, 1996
- Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.The Journal of cell biology, 1994
- Occludin: a novel integral membrane protein localizing at tight junctions.The Journal of cell biology, 1993