Patient-reported impact of chronic urticaria compared with psoriasis in theUnited States
Open Access
- 15 September 2016
- journal article
- research article
- Published by Informa UK Limited in Journal of Dermatological Treatment
- Vol. 28 (3), 229-236
- https://doi.org/10.1080/09546634.2016.1227421
Abstract
Purpose: Data are lacking on the burden of chronic idiopathic urticaria (CIU) versus other dermatologic conditions. This analysis compared the burden of chronic urticaria (CU, proxy for CIU) with psoriasis. Methods: Data from CU (N = 747) and psoriasis patients (N = 5107) came from 2010 to 2012 US National Health and Wellness Surveys. Outcomes included SF-12v2/SF-36v2 mental and physical component summary scores (MCS and PCS, respectively) and other health/activity-related measures. Results: MCS score was 44.7 for CU, and 48.2, 44.7 and 44.3 for mild/moderate/severe psoriasis, respectively (US norm = 50). PCS score was 43.8 for CU, and 46.5, 44.1 and 40.3 for mild/moderate/severe psoriasis. Health utility score was 0.67 for CU, and 0.72, 0.67 and 0.65 for mild/moderate/severe psoriasis. More CU patients reported depression (39%), anxiety (42%) and sleep difficulties (50%) than psoriasis patients (any severity). Overall work impairment was 29% for CU, and 19%, 26% and 31% for mild/moderate/severe psoriasis. Activities impairment was 39% for CU, and 28%, 37% and 43% for mild/moderate/severe psoriasis. CU and psoriasis patients had frequent healthcare visits. Conclusions: Patients with CU had impaired mental/physical health and work/non-work activities, similar to moderate-to-severe psoriasis patients. Results suggest that better disease management of CU is needed. This analysis should also reflect the significant burden of CIU.Keywords
Funding Information
- This study was funded by Novartis Pharmaceutical Corporation, East Hanover, NJ, USA, and Genentech, Inc., South San Francisco, CA, USA.
This publication has 23 references indexed in Scilit:
- Chronic idiopathic urticaria and anxiety symptomsJournal of Health Psychology, 2011
- Unmet clinical needs in chronic spontaneous urticaria. A GA2LEN task force report1Allergy, 2010
- Epidemiology of urticaria: a representative cross-sectional population surveyClinical and Experimental Dermatology, 2010
- Depression and Quality of Life in PsoriasisPostgraduate Medicine, 2009
- Quality of life in patients with chronic urticaria is differentially impaired and determined by psychiatric comorbidityBritish Journal of Dermatology, 2005
- Comparative study of the impact of chronic urticaria, psoriasis and atopic dermatitis on the quality of lifeBritish Journal of Dermatology, 2005
- Clinical and laboratory parameters in predicting chronic urticaria duration: a prospective study of 139 patientsAllergy, 2004
- The extent and nature of disability in different urticarial conditionsBritish Journal of Dermatology, 1999
- The impact of chronic urticaria on the quality of lifeBritish Journal of Dermatology, 1997
- The Validity and Reproducibility of a Work Productivity and Activity Impairment InstrumentPharmacoEconomics, 1993